Enter your search into one or more of the boxes below:
You can refine your search by selecting from any of the options below:
Autoimmune Diseases in Pediatric Gastroenterology: Proceedings of Falk Symposium Held in Basel, Switzerland, November 8-9, 2001: No. IV : International Falk Symposium on Paediatric Gastroenterology

Autoimmune Diseases in Pediatric Gastroenterology: Proceedings of Falk Symposium Held in Basel, Switzerland, November 8-9, 2001: No. IV : International Falk Symposium on Paediatric Gastroenterology (Hardback)

Printed to order. Despatched in 2-3 weeks.
Email me when back in stock


This book is the proceedings of the Falk Symposium No. 127 on 'Autoimmune Diseases in Paediatric Gastroenterology' (IV International Falk Symposium on Paediatric Gastroenterology), held in Basel, Switzerland, on November 8-9, 2001. The symposium focused on the role of the immune system, both the acquired and the innate systems, in inflammatory bowel disease (IBD) in children and adolescents. The innate system has an important fundamental role in host defence by initiating immune responses against potentially deleterious matter. However, a mutation within the innate system may elicit an immune response against the host: hence, an autoimmune response. Chronic autoimmune hepatitis occurs predominantly in young people, and especially in women. Immunological changes are conspicuous. Tissue antibodies are found in a large number of patients. This is a disease of disordered immunoregulation marked by a deficit in suppressor T cells causing the production of autoantibodies against specific hepatocyte surface antigen. Liver membrane protein is found in the sera of patients with autoimmune chronic acute hepatitis and with primary biliary cirrhosis (PBC).

The latter condition of progressive granulomatous destruction of intrahepatic bile ducts is, in many respects, analogous to the graft-versus-host syndrome where the immune system has become sensitized to foreign HLA-molecules. Primary sclerosing cholangitis (PSC) is another condition of unknown origin. All parts of the biliary tree can be involved in a chronic, fibrosing, inflammatory process that results in obliteration of the biliary tree and ultimately in biliary cirrhosis. About half of the patients also suffer from ulcerative colitis and rarely from Crohn's disease. Circulating antibodies to some antigens are found in obstructed portal tracts, as well as increased concentrations of biliary immune complexes in patients with PBC. In all three previous Falk symposia on paediatric gastroenterology, attention was focused on the role of the innate immune system in the aetiology of IBD. It has become increasingly clear in recent years that the innate system has a much more important and fundamental role in host defence. The decision to initiate an immune response is one of the major roles of the innate system.

Mutations within this system could transform it into becoming constitutively active, resulting in an inflammatory reaction and thus eliciting an autoimmune response. Following an introduction to the basic phenomena of autoimmunity, the proceedings discuss clinical aspects of autoimmune diseases. In particular, current knowledge and the state of the art about the diagnosis and treatment of the autoimmune diseases of the gastrointestinal tract are described by world-renowned experts. The book also contains the short presentations on selected topics, as well as abstracts of the mini-posters read by title, which were included in the symposium.

Medical & VeterinaryBrances of medicineGastroenterologyMedical & VeterinaryBrances of medicinePaediatric medicine Publisher: Kluwer Academic Publishers Publication Date: 01/09/2002 ISBN-13: 9780792387787  Details: Type: Hardback Format: Books
Availability: Printed to order. Despatched in 2-3 weeks.  

More books by F. Hadziselimovic

Leave Review


Delivery Options

All delivery times quoted are the average, and cannot be guaranteed. These should be added to the availability message time, to determine when the goods will arrive. During checkout we will give you a cumulative estimated date for delivery.

Location 1st Book Each additional book Average Delivery Time
UK Second Class Available free for ALL orders. No charge for each additional book. 3-7 Days
UK First Class £4.50 £1.00 1-2 Days
UK Courier £7.00 £1.00 1-2 Days
Western Europe** Courier £17.00 £3.00 2-3 Days
Western Europe** Airmail £5.00 £1.50 4-14 Days
USA / Canada Courier £20.00 £3.00 2-4 Days
USA / Canada Airmail £7.00 £3.00 4-14 Days
Rest of World Courier £22.50 £3.00 3-6 Days
Rest of World Airmail £8.00 £3.00 7-21 Days

** Includes Austria, Belgium, Denmark, France, Germany, Greece, Iceland, Irish Republic, Italy, Luxembourg, Netherlands, Portugal, Spain, Sweden and Switzerland.

Delivery Help & FAQs

Returns Information

If you are not completely satisfied with your purchase*, you may return it to us in its original condition with in 30 days of receiving your delivery or collection notification email for a refund. Except for damaged items or delivery issues the cost of return postage is borne by the buyer. Your statutory rights are not affected.

* For Exclusions and terms on damaged or delivery issues see Returns Help & FAQs

You might also like

MacSween's Pathology of the Liver
Alastair D. Burt; Linda D. Ferrell;...
Healing Digestive Disorders: Natural...
Andrew Gaeddert
Gut: new revised and expanded edition
Giulia Enders; David Shaw
Appetite and Food Intake: Central...
Ruth Harris
Latest Blog
ZED Books: The role of the independent publisher in a content-obsessed world

Indie publisher ZED Books have a radical approach to their books and their company structure. Here, they talk to us about the role independent publishers can play in a world of ever expanding (and less than reliable) information sources.

Blog - J R Wallis on Monsters as Metaphors

J R Wallis questions the conventional view of monsters as metaphors for the worries we have about the state of the world around us.

#FoylesFive: Creative Women

Meg from the Web Team tells us why she loves to learn about creative, dynamic women.

View all Blog Entries
Show/Hide Tweets
© W&G Foyle Ltd