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Brain Metallothionein in Neurological Disorders: Special Topic Issue: Neurosignals 1994, Vol. 3, No. 4
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Brain Metallothionein in Neurological Disorders: Special Topic Issue: Neurosignals 1994, Vol. 3, No. 4 (Paperback)

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Synopsis

The concentration of zinc has been shown to be altered in an extensive number of disorders of the central nervous system, including Alzheimer-type dementia, Down's syndrome, epilepsy, Friedreich's ataxia, multiple sclerosis, Parkinson's disease, schizophrenia, and alcoholism. The role of zinc metallothionein and other low-molecular-weight zinc-binding proteins in these conditions is currently being defined. Since several of these disorders are associated with oxidative stress, and since metallothionein is able to prevent the generation of free radicals, it is believed that cytokine-induced induction of metallothionein provides a long-lasting protection to avert oxidative damage. These topics are extensively discussed in the articles in this volume. Neuroanatomists, neurobiologists, neurochemists, neuropharmacologists, neurologists and psychiatrists will find this state-of-the-art publication a valuable addition to their libraries.

Medical & VeterinaryBrances of medicineNeurology & clinical neurophysiologyScience & MathematicsBiology, life sciencesBiochemistryProteinsScience & MathematicsBiology, life sciencesLife sciences: general issuesNeurosciencesScience & MathematicsBiology, life sciencesMolecular biology Publisher: S Karger AG Publication Date: 06/10/1994 ISBN-13: 9783805560573  Details: Type: Paperback Format: Books
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