Close
Enter your search into one or more of the boxes below:
You can refine your search by selecting from any of the options below:
Search
Calcium: The molecular basis of calcium action in biology and medicine

Calcium: The molecular basis of calcium action in biology and medicine (Paperback)

£271.50
Printed to order. Despatched in 2-3 weeks.
Email me when back in stock

Synopsis

The enormous and varied role of calcium in living systems is now widely appreciated by both cell biologists and clinicians. The identification and characterisation of new calcium binding proteins and regulatory pathways is matched by the recognition of the involvement of calcium binding proteins in a growing number of disease states. This book is intended to introduce clinicians to fundamental biological research, whilst at the same time attracting researchers to the clinical world. The publication of the book coincides with the elucidation of the complete Human Genomic Sequence. As a result of this, scientists now have access to an unprecedented array of data, from which new calcium binding proteins and hence new regulatory pathways will undoubtedly be discovered. It is a further aim of this book to provide a `key' to open the door to the new postgenomic era. The book is in three parts. The first section introduces the reader to the role of calcium in cell biology, providing an appreciation of how this small, simple, non-metabolisable agent can move rapidly and silently through the different cellular compartments, thereby influencing and controlling the fate of the cell. This section also illustrates and dissects the often-complex interplay between calcium and numerous agents in muscle and endocrine cells, neurons, hepatocytes, and platelets. In the second section the reader will discover the role of calcium and its partners in common diseases such as migraine and drug dependence. New classes of diseases such as annexinopathies, channelopathies, calcium-sensing disorders, and citrullinemia are discussed, and the authors give many new insights into the molecular mechanisms of the diseases, thereby explaining how and why they occur. Such information is clearly of primary importance for the pharmaceutical industry. New ideas and concepts of neurodegenerative diseases are introduced, which should stimulate new approaches. Clinicians will also have access, in a comprehensive and authoritative yet highly readable chapter, to data from recent large-scale clinical studies on the numerous and widely prescribed calcium antagonists. The final section gives information on new methods and devices for calcium imaging, and illustrates how calcium movement and change can be monitored and ingeniously utilised as a fast, cheap, and accurate drug screening instrument.

Medical & VeterinaryPre-clinical medicine: basic sciencesMedical geneticsMedical & VeterinaryPre-clinical medicine: basic sciencesPhysiology Publisher: Springer Publication Date: 01/11/2000 ISBN-13: 9780792364221  Details: Type: Paperback Format: Books
Availability: Printed to order. Despatched in 2-3 weeks.  

More books by Roland Pochet

More books by Rosario Donato

More books by J. Haiech

More books by Claus W. Heizmann

More books by Volker Gerke

Leave Review

Delivery

Delivery Options

All delivery times quoted are the average, and cannot be guaranteed. These should be added to the availability message time, to determine when the goods will arrive. During checkout we will give you a cumulative estimated date for delivery.

Location 1st Book Each additional book Average Delivery Time
UK Standard Delivery FREE FREE 3-5 Days
UK First Class £4.50 £1.00 1-2 Days
UK Courier £7.00 £1.00 1-2 Days
Western Europe** Courier £17.00 £3.00 2-3 Days
Western Europe** Airmail £5.00 £1.50 4-14 Days
USA / Canada Courier £20.00 £3.00 2-4 Days
USA / Canada Airmail £7.00 £3.00 4-14 Days
Rest of World Courier £22.50 £3.00 3-6 Days
Rest of World Airmail £8.00 £3.00 7-21 Days

** Includes Austria, Belgium, Denmark, France, Germany, Greece, Iceland, Irish Republic, Italy, Luxembourg, Netherlands, Portugal, Spain, Sweden and Switzerland.

Delivery Help & FAQs

Returns Information

If you are not completely satisfied with your purchase*, you may return it to us in its original condition with in 30 days of receiving your delivery or collection notification email for a refund. Except for damaged items or delivery issues the cost of return postage is borne by the buyer. Your statutory rights are not affected.

* For Exclusions and terms on damaged or delivery issues see Returns Help & FAQs

You might also like

Human Physiology
(Paperback)
Gillian Pocock; Christopher D....
 
 
£49.99
 
The Cell as a Machine
(Hardback)
Michael Sheetz; Hanry Yu
 
 
£69.99
 

Currently out of stock

Right Ventricular Physiology,...
(Books & other media combined)
Mark K. Friedberg; Andrew N. Redington
 
 
£126.00
 
Fundamentals of Anatomy & Physiology,...
(Paperback)
Frederic H. Martini; Judi L. Nath;...
 
 
£54.99
 

Currently out of stock

Latest Blog
The Mexican--US Border: Where the Imagination Flourishes…
19/01/2018

Tim Baker reflects on the literary impact of the Mexican-US border and lists some of his favourite novels set in this notorious region.

Johann Hari Takes Issue with the Concept of Self-Help
18/01/2018

Johann Hari explains why, in order to feel better, we must stop being 'you', in favour of being 'us', being 'we', becoming part of the group.

Jealousy, Rivalry, Insecurity, Frustration... Non Pratt Explores the World of Female Teenage Friendships
16/01/2018

Non explores friendship in YA novels and especially those that depict the imperfect middle ground.

View all Blog Entries
Twitter
Show/Hide Tweets
© W&G Foyle Ltd