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Chemical Carcinogenesis: Models and Mechanisms

Chemical Carcinogenesis: Models and Mechanisms (Hardback)

£72.00
Unavailable. This title is Out of Print.
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Synopsis

About two centuries after the communication by Sir Percival Pott that the "chimney sweeper disease" was a cancer and its suggestion that active compounds of soot were the causative agents, and about one century after the description of urinary bladder cancer in dye workers, an enormous number of substances have been synthesized and have probably come into contact with man. Research in cancer prevention is of primary importance, and may receive continuous support from new discoveries on cancer etiology and pathogenesis. If one accepts the multistage model of chemical carcinogenesis, one has also to accept that many events occur between the contact of carcino- genic compounds and their specific targets and the development of a clinically recognizable neoplasm. Thus, animal studies become essential to elucidate the different steps by which chemical carcinogens induce neoplasia. The analysis of these steps and the comparative evaluation of experimental models is essential to an understanding of pathogenesis.

Medical & VeterinaryBrances of medicineDiseases & disordersOncology Publisher: Kluwer Academic Publishers Group Publication Date: 01/01/1989 ISBN-13: 9780306430855  Details: Type: Hardback Format: Books
Availability: Unavailable. This title is Out of Print.  

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