Close
Enter your search into one or more of the boxes below:
You can refine your search by selecting from any of the options below:
Search
Coronary Tone in Ischemic Heart Disease

Coronary Tone in Ischemic Heart Disease (Hardback)

£132.00
Printed to order. Despatched in 2-3 weeks.
Email me when back in stock

Synopsis

W. KUPPER Coronary artery vasoconstriction is not only the mechanism responsible for Prinzmetal's variant angina, but may also be involved in stable angina pectoris and myocardial infarction. However, the underlying patho-physiological mecha- nisms and the importance of coronary vasoconstriction in these syndromes is still largely unknown. Several hypotheses have been proposed. Sympathetic nervous activity plays a key role in the regulation of coronary blood flow, but mechanical or humoral constrictive factors may be active as well. a-adrenergic tone Adrenergic nerve fibers accompany coronary vessels of any size. The stimulation of cardiac sympathetic nerves causes an increase in coronary blood flow. If, however, chronotropic and inotropic effects of adrenergic stimulation are sup- pressed pharmacologically by beta-adrenoceptor blockade, a reduction in flow is observed. Thus, the primary effect of sympathetic stimulation on the coronary arteries is the alpha-adrenergic mediated vasoconstriction. Functionally inner- vated alpha-adrenoceptors have been documented both in large coronary con- ductance arteries and in the small resistance vessels.

Animal studies and a human study have documented that a permanent constrictor tone is present on the coronary circulation both at rest and during exercise; this condition could be prevented with alpha-adrenoceptor blockade or was absent after heart transplan- tation. Therefore, alpha-adrenoceptor mediated coronary constriction is an at- tractive hypothesis as a possible pathophysiological mechanism of inappropriate coronary vasoconstriction and cororiary vasospasm.

Medical & VeterinaryBrances of medicineCardiovascular medicine Publisher: Kluwer Academic Publishers Publication Date: 31/08/1984 ISBN-13: 9780898386462  Details: Type: Hardback Format: Books
Availability: Printed to order. Despatched in 2-3 weeks.  

More books by W. Kupper

More books by W. Bleifeld

More books by R.N. MacAlpin

Leave Review

Delivery

Delivery Options

All delivery times quoted are the average, and cannot be guaranteed. These should be added to the availability message time, to determine when the goods will arrive. During checkout we will give you a cumulative estimated date for delivery.

Location 1st Book Each additional book Average Delivery Time
UK Standard Delivery FREE FREE 3-5 Days
UK First Class £4.50 £1.00 1-2 Days
UK Courier £7.00 £1.00 1-2 Days
Western Europe** Courier £17.00 £3.00 2-3 Days
Western Europe** Airmail £5.00 £1.50 4-14 Days
USA / Canada Courier £20.00 £3.00 2-4 Days
USA / Canada Airmail £7.00 £3.00 4-14 Days
Rest of World Courier £22.50 £3.00 3-6 Days
Rest of World Airmail £8.00 £3.00 7-21 Days

** Includes Austria, Belgium, Denmark, France, Germany, Greece, Iceland, Irish Republic, Italy, Luxembourg, Netherlands, Portugal, Spain, Sweden and Switzerland.

Delivery Help & FAQs

Returns Information

If you are not completely satisfied with your purchase*, you may return it to us in its original condition with in 30 days of receiving your delivery or collection notification email for a refund. Except for damaged items or delivery issues the cost of return postage is borne by the buyer. Your statutory rights are not affected.

* For Exclusions and terms on damaged or delivery issues see Returns Help & FAQs

You might also like

Acute and Critical Care Echocardiography
(Paperback)
Claire Colebourn; Jim Newton
 
 
£70.00
 
Manual of Chronic Total Occlusion...
(Paperback)
Emmanouil Brilakis
 
 
£71.95
 
Vital Remains: Winston Wicomb, the...
(Hardback)
Winston Wicomb; Amos van der Merwe
 
 
£20.00
 
Latest Blog
Why Little Women is the Perfect Christmas Read
15/12/2017

Publisher of the Macmillan Collectors Library, Harriet Sanders, celebrates the arrival on tv this Christmas of Little Women

#FoylesFive: Foreign Languages Part Two
13/12/2017

Our knowledgeable Languages Department have put together a great selection of books, to help share the magic of reading in every language. Here are their Dutch, Russian and Polish selections.

#FoylesFive: The Last Jedi
12/12/2017

As Star Wars: The Last Jedi drops out of hyperspace and into a cinema near you, Matt from our Web Team gives us his selection of the best Last Jedi books.

View all Blog Entries
Twitter
Show/Hide Tweets
© W&G Foyle Ltd