Enter your search into one or more of the boxes below:
You can refine your search by selecting from any of the options below:
Cytoskeleton and Small G Proteins

Cytoskeleton and Small G Proteins (Paperback)

Printed to order. Despatched in 2-3 weeks.
Email me when back in stock


Animal cells present an extreme variability in their shapes in relation to their physiological properties. For instance, fibroblastic cells are tightly attached to the extra-cellular matrix and display a flattened, spindle-shaped morphology. Neuronal cells self-organize as a network through a complex branching of dendrites and a long axonal extension. Resting peripheral blood lymphocytes are poorly adhesive and maintain a spherical, smooth shape, while macroph- ages produce many pseudopodal extensions involved in the recognition of foreign molecules. In addition to the variability of the morphology of the cells that constitute different organs, many cell types also modify dynamically their morphology in response to environmental changes, leading to differential cell motility, migration, adhesion, polarity or intercellular contacts. This wide plasticity of cell morphology is promoted and maintained by the cytoskeleton, which is composed of the three interconnected actin micro filaments, tubulin microtubules and intermediate filaments networks, all capable of assembly and disassembly.

Over the past few years, the Rho family of Ras-like GTPases emerged as key proteins that mediate extracellular signalling pathways leading to the forma- tion of polymerized actin-containing structures such as ruffles, lamellipodia and filopodia. Since the discovery of the first member RhoA in 1985, 13 mem- bers have so far been characterized in human cells. Most of Rho proteins are highly conserved between species as distant as yeast, slime mold, insects and mammals, which points to their fundamental role in cellular physiology.

Medical & VeterinaryBrances of medicineDiseases & disordersOncologyScience & MathematicsBiology, life sciencesBiochemistryScience & MathematicsBiology, life sciencesCellular biology or cytologyScience & MathematicsBiology, life sciencesMolecular biology Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Publication Date: 08/10/2012 ISBN-13: 9783642636592  Details: Type: Paperback Format: Books
Availability: Printed to order. Despatched in 2-3 weeks.  

More books by Philippe Jeanteur

Leave Review


Delivery Options

All delivery times quoted are the average, and cannot be guaranteed. These should be added to the availability message time, to determine when the goods will arrive. During checkout we will give you a cumulative estimated date for delivery.

Location 1st Book Each additional book Average Delivery Time
UK Second Class Available free for ALL orders. No charge for each additional book. 3-7 Days
UK First Class £4.50 £1.00 1-2 Days
UK Courier £7.00 £1.00 1-2 Days
Western Europe** Courier £17.00 £3.00 2-3 Days
Western Europe** Airmail £5.00 £1.50 4-14 Days
USA / Canada Courier £20.00 £3.00 2-4 Days
USA / Canada Airmail £7.00 £3.00 4-14 Days
Rest of World Courier £22.50 £3.00 3-6 Days
Rest of World Airmail £8.00 £3.00 7-21 Days

** Includes Austria, Belgium, Denmark, France, Germany, Greece, Iceland, Irish Republic, Italy, Luxembourg, Netherlands, Portugal, Spain, Sweden and Switzerland.

Delivery Help & FAQs

Returns Information

If you are not completely satisfied with your purchase*, you may return it to us in its original condition with in 30 days of receiving your delivery or collection notification email for a refund. Except for damaged items or delivery issues the cost of return postage is borne by the buyer. Your statutory rights are not affected.

* For Exclusions and terms on damaged or delivery issues see Returns Help & FAQs

You might also like

Radiation Therapy Treatment Effects:...
Bridget F. Koontz
Pretty Sick: The Beauty Guide for...
Caitlin Kiernan
Dear Friend: Letters of ...
Gina Mulligan
Latest Blog
Caroline Taggart on Why Punctuation Can be Surprisingly Exciting

Caroline Taggart explains the versatility of punctuation.

Under the Knife: Recreating the Grimy World of Victorian Surgery

Lindsey describes how she made the trailer for her debut The Butchering Art in order to see how the sights, sounds, and smells of this gruesome period in medical history would translate onto the screen.

The Sky Doesn't Have to be Blue: Steve Antony on Life as a Colour Blind Illustrator

Steve explains what it's like to be a colour blind illustrator and why the sky doesn't have to be blue.

View all Blog Entries
Show/Hide Tweets
© W&G Foyle Ltd