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Multiple Testing Procedures with Applications to Genomics
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Multiple Testing Procedures with Applications to Genomics (Hardback)

£179.99
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Synopsis

This book establishes the theoretical foundations of a general methodology for multiple hypothesis testing and discusses its software implementation in R and SAS. These are applied to a range of problems in biomedical and genomic research, including identification of differentially expressed and co-expressed genes in high-throughput gene expression experiments; tests of association between gene expression measures and biological annotation metadata; sequence analysis; and genetic mapping of complex traits using single nucleotide polymorphisms. The procedures are based on a test statistics joint null distribution and provide Type I error control in testing problems involving general data generating distributions, null hypotheses, and test statistics.

Medical & VeterinaryScience & MathematicsBiology, life sciencesLife sciences: general issuesGenetics non-medicalScience & MathematicsMathematicsProbability & statistics Publisher: Springer-Verlag New York Inc. Publication Date: 19/12/2007 ISBN-13: 9780387493169  Details: Type: Hardback Format: Books
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