Enter your search into one or more of the boxes below:
You can refine your search by selecting from any of the options below:
Mycoplasma Infection of Cell Cultures

Mycoplasma Infection of Cell Cultures (Paperback)

Printed to order. Despatched in 2-3 weeks.
Email me when back in stock


If one were to design the ideal nuisance for cell cultures, the resultant might well be similar to mycoplasmas. These micro- organisms are very prevalent in nature, being found in the oral cavity, blood, the mucous membranes of the respiratory and uro- genital tract and other tissues of both man and animals. They are relatively difficult to detect microbiologically and chemically. Lacking cell walls, they do not routinely produce turbidity in cell cultures and are resistant to antibiotics that act on cell walls. Mycoplasmas grow to high titers in cell cultures. Concen- 7 8 trations of 10-10 colony forming units per ml of supernatant medium are representative. Additionally, more numbers are attached to cell membranes. Further, mycoplasmas have been shown to mimic in vitro effects of viruses and toxic chemicals. In various cell culture systems, mycoplasmas have been known to cause cell death, decrease or increase cell growth, affect virus tite~s, induce interferon, cause chromosome damage, induce transformation, cyto- pathic effects, alter phenotypic expression, and significantly alter metabolic pathways and products of cells. The presence of such high concentrations of mycoplasmas in cell cultures constitutes a true in vitro infection. Such infected cell cultures, with a 8 9 total of 10 _10 or more actively metabolizing mycoplasmas, have no place in controlled, standardized cell culture procedures. Numerous reports have been published on mycoplasma assay pro- cedures, effects of infection, and preventive and elimination measures.

Medical & VeterinaryPre-clinical medicine: basic sciencesAnatomy Publisher: Springer-Verlag New York Inc. Publication Date: 01/03/1978 ISBN-13: 9781468498769  Details: Type: Paperback Format: Books
Availability: Printed to order. Despatched in 2-3 weeks.  

More books by G. McGarrity

Leave Review


Delivery Options

All delivery times quoted are the average, and cannot be guaranteed. These should be added to the availability message time, to determine when the goods will arrive. During checkout we will give you a cumulative estimated date for delivery.

Location 1st Book Each additional book Average Delivery Time
UK Standard Delivery FREE FREE 3-5 Days
UK First Class £4.50 £1.00 1-2 Days
UK Courier £7.00 £1.00 1-2 Days
Western Europe** Courier £17.00 £3.00 2-3 Days
Western Europe** Airmail £5.00 £1.50 4-14 Days
USA / Canada Courier £20.00 £3.00 2-4 Days
USA / Canada Airmail £7.00 £3.00 4-14 Days
Rest of World Courier £22.50 £3.00 3-6 Days
Rest of World Airmail £8.00 £3.00 7-21 Days

** Includes Austria, Belgium, Denmark, France, Germany, Greece, Iceland, Irish Republic, Italy, Luxembourg, Netherlands, Portugal, Spain, Sweden and Switzerland.

Delivery Help & FAQs

Returns Information

If you are not completely satisfied with your purchase*, you may return it to us in its original condition with in 30 days of receiving your delivery or collection notification email for a refund. Except for damaged items or delivery issues the cost of return postage is borne by the buyer. Your statutory rights are not affected.

* For Exclusions and terms on damaged or delivery issues see Returns Help & FAQs

You might also like

Physics of the Body
John R. Cameron; James G. Skofronick;...
Guy Orchard; Brian Nation
Inderbir Singh's Textbook of Human...
Pritha S Bhuiyan; Lakshmi Rajgopal; K...
Principles of Clinical Genetics
Yogesh Ashok Sontakke
Latest Blog
#FoylesFive: Foreign Languages Part One

Our knowledgeable and fabulous Languages Department have put together a great selection of books, to help share the magic of reading in every language. First up we have books in Italian, Portugese and Swedish.

Crime, Responsibility and Morality: The Impact of Siberian Exile on Fyodor Dostoevsky

Daniel describes how Siberian exile was the great writer Fyodor Dostoevsky’s foundational experience as an author and thinker.

#FoylesFive: Classical Languages

The team from our Languages Department pick a selection of titles on language and its historical and contemporary importance.

View all Blog Entries
Show/Hide Tweets
© W&G Foyle Ltd