Close
Enter your search into one or more of the boxes below:
You can refine your search by selecting from any of the options below:
Search
Peptidomimetics Protocols

Peptidomimetics Protocols (Hardback)

£123.00
Printed to order. Despatched in 2-3 weeks.
Email me when back in stock

Synopsis

Many physiologically important receptors and enzymes are regulated by their endogenous ligands and inhibitors. Nature chose to utilize these p- tides as chemical switches since they can be efficiently synthesized and - graded in cells, thus providing an immediate response to a fast changing environment. Such properties, so critical in cell survival, make peptides less than ideal drug candidates. Other frequently desired properties in drug m- ecules include oral bioavailability, the ability to cross membranes, including the blood-brain barrier, and sufficient stability for administration 1-2 times a day. In spite of these obstacles, some natural peptides and proteins are ind- putably successful medicines and have become drugs of choice. Further - vances in peptide-based pharmaceuticals are critically dependent on both new delivery methods and new chemical approaches to the conversion of these molecules to druglike entities. In addition, peptides are also the natural sta- ing points for optimization of their pharamacological and chemical prop- ties, which may lead to superior drugs.

Peptidomimetics Protocols deals with both aspects of peptide pharmaceuticals, through the tools of modern s- thetic and medicinal chemistry. The last decade has witnessed a steady stream of new synthetic approaches to peptide mimetics, compounds that replace phy- ologically vulnerable peptide functionalities with chemical modules of - creased stability and cellular penetration. The chapters have been written by both academic and industrial chemists, and focus on the practical synthetic preparation of peptide mimetics.

Medical & VeterinaryBrances of medicinePharmacology Publisher: Humana Press Inc. Publication Date: 19/10/1998 ISBN-13: 9780896035171  Details: Type: Hardback Format: Books
Availability: Printed to order. Despatched in 2-3 weeks.  

More books by Wieslaw M. Kazmierski

Leave Review

Delivery

Delivery Options

All delivery times quoted are the average, and cannot be guaranteed. These should be added to the availability message time, to determine when the goods will arrive. During checkout we will give you a cumulative estimated date for delivery.

Location 1st Book Each additional book Average Delivery Time
UK Second Class Available free for ALL orders. No charge for each additional book. 3-7 Days
UK First Class £4.50 £1.00 1-2 Days
UK Courier £7.00 £1.00 1-2 Days
Western Europe** Courier £17.00 £3.00 2-3 Days
Western Europe** Airmail £5.00 £1.50 4-14 Days
USA / Canada Courier £20.00 £3.00 2-4 Days
USA / Canada Airmail £7.00 £3.00 4-14 Days
Rest of World Courier £22.50 £3.00 3-6 Days
Rest of World Airmail £8.00 £3.00 7-21 Days

** Includes Austria, Belgium, Denmark, France, Germany, Greece, Iceland, Irish Republic, Italy, Luxembourg, Netherlands, Portugal, Spain, Sweden and Switzerland.

Delivery Help & FAQs

Returns Information

If you are not completely satisfied with your purchase*, you may return it to us in its original condition with in 30 days of receiving your delivery or collection notification email for a refund. Except for damaged items or delivery issues the cost of return postage is borne by the buyer. Your statutory rights are not affected.

* For Exclusions and terms on damaged or delivery issues see Returns Help & FAQs

You might also like

Foundations of Analytical Chemistry: ...
(Books & other media combined)
Miguel Valcarcel Cases; Angela I....
 
 
£48.99
 
Cationic Amphiphiles: Self-Assembling...
(Hardback)
Ferdinand Devinsky; Martin Pisarcik;...
 
 
£90.50
 
Cannabinoid Pharmacology: Volume 80
(Hardback)
David Kendall; Stephen Alexander
 
 
£155.00
 
Prescriber's Guide: Antidepressants:...
(Paperback)
Stephen M. Stahl
 
 
£49.99
 

Currently out of stock

Latest Blog
#FoylesFave: Dr Seuss
25/09/2017

Matt from our Web Team is very silly. Maybe this explains his love for Dr Seuss, especially this new glow in the dark edition of What Was I Scared Of?

Read an Extract from A Skinful of Shadows
21/09/2017

Read an extract from the eagerly awaited new novel by the Costa-winning Frances Hardinge, A Skinful of Shadows.

#FoylesFive: Elsewhere-Elsewhen
18/09/2017

Jen from the Web Team shares a selection of books that will transport the reader to another time and place.

View all Blog Entries
Twitter
Show/Hide Tweets
© W&G Foyle Ltd