Close
Enter your search into one or more of the boxes below:
You can refine your search by selecting from any of the options below:
Search
The Somatotrophic Axis and the Reproductive Process in Health and Disease: Serona Symposia, USA, Norwell, Massachusetts

The Somatotrophic Axis and the Reproductive Process in Health and Disease: Serona Symposia, USA, Norwell, Massachusetts (Hardback)

£72.00
To Order. Estimated despatch in 1-3 weeks.
Email me when back in stock

Synopsis

For many years now, our understanding of the somatotrophic and reproduc- tive axes has evolved essentially independently, both fields of study reaching a highly advanced, although far from complete, level of under- standing. Along the way, however, it became apparent that in some circumstances the reproductive and somatotrophic axes may be inter- dependent. Inklings to this effect were at times feeble and at other times more convincing. Among those inklings are the clinical recognition by pediatric endocrinologists of the apparent association between isolated GH deficiency and delayed puberty, as well as of the apparent permissive, pUberty-promoting property of GH. Equally important is a body of experi- mental studies establishing the ovary of multiple species as a site of GH reception and action. Arguing against an essential role for GH in the reproductive process is the observation that individuals who have GH resistance of the Laron variety are fertile arid that isolated GH deficiency does not constitute an absolute barrier to the attainment of sexual maturation and fertility.

The intraovarian insulin-like growth factor (IGF) hypothesis proposes that IGFs may serve as amplifiers of gonadotropin action. Although the dependence of intraovarian IGFs on systemic GH action has never been unequivocally demonstrated, that leap of faith has often been made. The intraovarian IGF hypothesis serves as the rationale for the adjunctive use of GH in the induction of ovulation.

More books by Eli Y. Adashi

More books by Michael O. Thorner

Leave Review

Delivery

Delivery Options

All delivery times quoted are the average, and cannot be guaranteed. These should be added to the availability message time, to determine when the goods will arrive. During checkout we will give you a cumulative estimated date for delivery.

Location 1st Book Each additional book Average Delivery Time
UK Standard Delivery FREE FREE 3-5 Days
UK First Class £4.50 £1.00 1-2 Days
UK Courier £7.00 £1.00 1-2 Days
Western Europe** Courier £17.00 £3.00 2-3 Days
Western Europe** Airmail £5.00 £1.50 4-14 Days
USA / Canada Courier £20.00 £3.00 2-4 Days
USA / Canada Airmail £7.00 £3.00 4-14 Days
Rest of World Courier £22.50 £3.00 3-6 Days
Rest of World Airmail £8.00 £3.00 7-21 Days

** Includes Austria, Belgium, Denmark, France, Germany, Greece, Iceland, Irish Republic, Italy, Luxembourg, Netherlands, Portugal, Spain, Sweden and Switzerland.

Delivery Help & FAQs

Returns Information

If you are not completely satisfied with your purchase*, you may return it to us in its original condition with in 30 days of receiving your delivery or collection notification email for a refund. Except for damaged items or delivery issues the cost of return postage is borne by the buyer. Your statutory rights are not affected.

* For Exclusions and terms on damaged or delivery issues see Returns Help & FAQs

You might also like

Histopathology
(Paperback)
Guy Orchard; Brian Nation
 
 
£36.99
 
Anatomy and Physiology in Healthcare
(Paperback)
Paul Marshall; Beverly Gallacher; Jim...
 
 
£29.99
 
Cell Physiology
(Hardback)
Gloria Doran
 
 
£110.75
 

Currently out of stock

Methods in Molecular Biophysics:...
(Hardback)
Nathan R. Zaccai; Igor N. Serdyuk;...
 
 
£54.99
 
Latest Blog
Why Little Women is the Perfect Christmas Read
15/12/2017

Publisher of the Macmillan Collectors Library, Harriet Sanders, celebrates the arrival on tv this Christmas of Little Women

#FoylesFive: Foreign Languages Part Two
13/12/2017

Our knowledgeable Languages Department have put together a great selection of books, to help share the magic of reading in every language. Here are their Dutch, Russian and Polish selections.

#FoylesFive: The Last Jedi
12/12/2017

As Star Wars: The Last Jedi drops out of hyperspace and into a cinema near you, Matt from our Web Team gives us his selection of the best Last Jedi books.

View all Blog Entries
Twitter
Show/Hide Tweets
© W&G Foyle Ltd