Close
Enter your search into one or more of the boxes below:
You can refine your search by selecting from any of the options below:
Search
The Tumor Microenvironment

The Tumor Microenvironment (Paperback)

£230.00
Printed to order. Despatched in 2-3 weeks.
Email me when back in stock

Synopsis

The fact that tumors are composed of both tumor cells and host cells has long been known. These tumor-associated cells include vascular endothelial cells and pe- cytes, as well as inflammatory cells such as neutrophils, monocytes, macrophages, mast cells and eosinophils, and lymphocytes. The tumor cells also interact with stromal cells and with elements of the tissue extracellular matrix. What has been less appreciated is the role that these cells could have in modulating the growth, invasion, and metastasis of the tumor. Early on, the elements of what we now call the tumor microenvironment were considered to be more or less innocent bysta- ers to the role of the tumor cells as they grew and invaded local sites. Today, there is an increased understanding of the critical role of the tumor microenvironment as dramatically influencing the course of tumor development and dissemination. This volume represents a superb compilation of the latest thoughts and data regarding the role of each essential component of the tumor microenvironment in cancer development and progression. Perhaps, the earliest recognition of the role of nonmalignant cells as cancer re- lators was the recognition that lymphocytes can participate in what was termed "immune surveillance" in the 1960s. Our understanding of tumor immunity has improved markedly since then, and there are now successful clinical studies sh- ing the potential use of immune-based therapies in cancer treatment.

Medical & VeterinaryBrances of medicineDiseases & disordersOncologyMedical & VeterinaryBrances of medicinePharmacology Publisher: Humana Press Inc. Publication Date: 06/11/2012 ISBN-13: 9781461426608  Details: Type: Paperback Format: Books
Availability: Printed to order. Despatched in 2-3 weeks.  

Rebecca Bagley is a senior scientist at Genzyme Corporation and has worked in the biotechnology industry for 20 years with degrees in biology from Wellesley College and Harvard University. Her expertise in drug development spans a wide range of approaches including immunotherapies, gene and protein therapies, and small molecule delivery with publications in journals such as Molecular Cancer Therapeutics, Cancer Research, and Microvascular Research . Her current research focuses on stem cells, tumor vasculature, and target validation.

More books by Rebecca G. Bagley

Leave Review

Delivery

Delivery Options

All delivery times quoted are the average, and cannot be guaranteed. These should be added to the availability message time, to determine when the goods will arrive. During checkout we will give you a cumulative estimated date for delivery.

Location 1st Book Each additional book Average Delivery Time
UK Standard Delivery FREE FREE 3-5 Days
UK First Class £4.50 £1.00 1-2 Days
UK Courier £7.00 £1.00 1-2 Days
Western Europe** Courier £17.00 £3.00 2-3 Days
Western Europe** Airmail £5.00 £1.50 4-14 Days
USA / Canada Courier £20.00 £3.00 2-4 Days
USA / Canada Airmail £7.00 £3.00 4-14 Days
Rest of World Courier £22.50 £3.00 3-6 Days
Rest of World Airmail £8.00 £3.00 7-21 Days

** Includes Austria, Belgium, Denmark, France, Germany, Greece, Iceland, Irish Republic, Italy, Luxembourg, Netherlands, Portugal, Spain, Sweden and Switzerland.

Delivery Help & FAQs

Returns Information

If you are not completely satisfied with your purchase*, you may return it to us in its original condition with in 30 days of receiving your delivery or collection notification email for a refund. Except for damaged items or delivery issues the cost of return postage is borne by the buyer. Your statutory rights are not affected.

* For Exclusions and terms on damaged or delivery issues see Returns Help & FAQs

You might also like

The Essential Guide to Skin Cancer
(Paperback)
Ian Walton
 
 
£9.99
 
Understanding BRCA: Living with the...
(Paperback)
Clarissa Foster
 
 
£14.99
 
Tumors of the Intestines
(Hardback)
Elizabeth A. Montgomery; Rhonda K....
 
 
£162.00
 
Latest Blog
The Satisfaction of a Good Puzzle
21/11/2017

Alex Bellos extols the virtues of the puzzle, especially those from the great puzzle masters of Japan, and selects some of his favourite puzzle books.

#FoylesFive: Swap Snowflakes for Stardust
17/11/2017

Swap snowflakes for stardust this Christmas with some recommends that are out of this world, from Jamie-Lee from our Birmingham branch.

Read an extract of The Book of the Year
15/11/2017

Behold The Book of the Year, by the “No Such Thing As A Fish” podcasters a.k.a the QI Elves. The book is a surreal, silly and wonderful compendium of irreverent and topical facts that show 2017 in a unique light.

View all Blog Entries
Twitter
Show/Hide Tweets
© W&G Foyle Ltd