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Biomolecular Crystallography: Principles, Practice, and Application to Structural Biology

Biomolecular Crystallography: Principles, Practice, and Application to Structural Biology (Hardback)

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Synopsis

Synthesizing over thirty years of advances into a comprehensive textbook, Biomolecular Crystallography describes the fundamentals, practices, and applications of protein crystallography. Deftly illustrated in full-color by the author, the text describes mathematical and physical concepts in accessible and accurate language. It distills key concepts for understanding the practice and analysis of protein crystal structures and contains examples of biologically-relevant molecules, complexes, and drug target structures. Biomolecular Crystallography will be a valuable resource for advanced undergraduate and graduate students and practitioners in structural biology, crystallography, and structural bioinformatics.

Bernhard Rupp is the CEO and founder of q.e.d. life science discoveries in California. Dr. Rupp established the protein drug target crystallography group at the University of California Lawrence Livermore National Laboratory in 1993 and expanded it into high throughput crystallization and structural genomics with focus on drug target structures and structure guided drug discovery. He was also a founding member of TB Structural Genomics Consortium. Dr. Rupp is a consultant for several US biotech ventures, universities, and instrument manufacturers. He is a member of the U.S. National Academy of Sciences Committee for Crystallography and NAS Keck Futures Initiatives panel. Dr. Rupp lectures regularly at NSF sponsored workshops on Biomolecular Crystallography and at the EMBO PEPC workshops on protein expression,

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