Close
Enter your search into one or more of the boxes below:
You can refine your search by selecting from any of the options below:
Search
Membrane Protein Protocols: Expression, Purification, and Characterization

Membrane Protein Protocols: Expression, Purification, and Characterization (Hardback)

£115.50
Printed to order. Despatched in 2-3 weeks.
Email me when back in stock

Synopsis

Knowledge of the three-dimensional structure of a protein is absolutely required for the complete understanding of its function. The spatial orientation of amino acids in the active site of an enzyme demonstrates how substrate specificity is defined, and assists the medicinal chemist in the design of s- cific, tight-binding inhibitors. The shape and contour of a protein surface hints at its interaction with other proteins and with its environment. Structural ana- sis of multiprotein complexes helps to define the role and interaction of each individual component, and can predict the consequences of protein mutation or conditions that promote dissociation and rearrangement of the complex. Determining the three-dimensional structure of a protein requires milligram quantities of pure material. Such quantities are required to refine crystallization conditions for X-ray analysis, or to overcome the sensitivity limitations of NMR spectroscopy. Historically, structural determination of proteins was limited to those expressed naturally in large amounts, or derived from a tissue or cell source inexpensive enough to warrant the use of large quantities of cells. H- ever, with the advent of the techniques of modern gene expression, many p- teins that are constitutively expressed in minute amounts can become accessible to large-scale purification and structural analysis.

Science & MathematicsBiology, life sciences Publisher: Humana Press Inc. Publication Date: 29/05/2003 ISBN-13: 9781588291240  Details: Type: Hardback Format: Books
Availability: Printed to order. Despatched in 2-3 weeks.  

More books by Barry Selinsky

Leave Review

Delivery

Delivery Options

All delivery times quoted are the average, and cannot be guaranteed. These should be added to the availability message time, to determine when the goods will arrive. During checkout we will give you a cumulative estimated date for delivery.

Location 1st Book Each additional book Average Delivery Time
UK Second Class Available free for ALL orders. No charge for each additional book. 3-7 Days
UK First Class £4.50 £1.00 1-2 Days
UK Courier £7.00 £1.00 1-2 Days
Western Europe** Courier £17.00 £3.00 2-3 Days
Western Europe** Airmail £5.00 £1.50 4-14 Days
USA / Canada Courier £20.00 £3.00 2-4 Days
USA / Canada Airmail £7.00 £3.00 4-14 Days
Rest of World Courier £22.50 £3.00 3-6 Days
Rest of World Airmail £8.00 £3.00 7-21 Days

** Includes Austria, Belgium, Denmark, France, Germany, Greece, Iceland, Irish Republic, Italy, Luxembourg, Netherlands, Portugal, Spain, Sweden and Switzerland.

Delivery Help & FAQs

Returns Information

If you are not completely satisfied with your purchase*, you may return it to us in its original condition with in 30 days of receiving your delivery or collection notification email for a refund. Except for damaged items or delivery issues the cost of return postage is borne by the buyer. Your statutory rights are not affected.

* For Exclusions and terms on damaged or delivery issues see Returns Help & FAQs

You might also like

Care of the Species: Races of Corn ...
(Paperback)
John Hartigan
 
 
£21.99
 
The Complete Illustrated World...
(Hardback)
Martin Walters
 
 
£12.99
 
The Brain as a Tool: A...
(Hardback)
Ray W. Guillery
 
 
£39.99
 
Latest Blog
Caroline Taggart on Why Punctuation Can be Surprisingly Exciting
18/10/2017

Caroline Taggart explains the versatility of punctuation.

Under the Knife: Recreating the Grimy World of Victorian Surgery
17/10/2017

Lindsey describes how she made the trailer for her debut The Butchering Art in order to see how the sights, sounds, and smells of this gruesome period in medical history would translate onto the screen.

The Sky Doesn't Have to be Blue: Steve Antony on Life as a Colour Blind Illustrator
13/10/2017

Steve explains what it's like to be a colour blind illustrator and why the sky doesn't have to be blue.

View all Blog Entries
Twitter
Show/Hide Tweets
© W&G Foyle Ltd