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Peptide and Protein Drug Analysis

Peptide and Protein Drug Analysis (Hardback)

£160.00
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Synopsis

Furthering efforts to simulate the potency and specificity exhibited by peptides and proteins in healthy cells, this remarkable reference supplies pharmaceutical scientists with a wealth of techniques for tapping the enormous therapeutic potential of these molecules-providing a solid basis of knowledge for new drug design.

Provides a broad, comprehensive overview of peptides and proteins as mediators of cell movement, proliferation, differentiation, and communication.

Written by more than 50 leading international authorities, Peptides and Protein Drug Analysis

discusses strategies for dealing with the complexity of peptides and proteins in conformational flexibility and amino acid sequence variability



analyzes drug formulations facilitated by solid-phase peptide synthesis and recombinant DNA technology



examines chemical purity analysis by high-pressure chromatographic, capillary electrophoretic, gel electrophoretic, and isoelectric focusing methods



highlights drug design elements derived from protein folding, bioinformatics, and computational chemistry



demonstrates uses of unnatural mutagenesis and combinatorial chemistry



explores mass spectrometry, protein sequence, and carbohydrate analysis



illustrates bioassays and other new functional analysis methods



surveys spectroscopic techniques such as ultraviolet, fluorescence, Fourier transform infrared, and nuclear magnetic resonance (NMR)



addresses ways of distinguishing between levels of therapeutic and endogenous agents in cells



reviews structural analysis tools such as ultracentrifugation and light, X-ray, and neutron scattering



and more!

Featuring over 3400 bibliographic citations and more than 500 tables, equations, and illustrations, Peptide and Protein Drug Analysis is a must-read resource for pharmacists; pharmacologists; analytical, organic, and pharmaceutical chemists; cell and molecular biologists; biochemists; and upper-level undergraduate and graduate students in these disciplines.

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Location 1st Book Each additional book Average Delivery Time
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