Close
Enter your search into one or more of the boxes below:
You can refine your search by selecting from any of the options below:
Search
Studies on Retinal and Choroidal Disorders

Studies on Retinal and Choroidal Disorders (Hardback)

£215.00
Printed to order. Despatched in 2-3 weeks.
Email me when back in stock

Synopsis

Studies on Retinal and Choroidal Disorders examines the role that oxidative and nitrosative stress plays in the complex physiology and pathophysiology of the retina and choroid. Both the basic science researcher and the clinical practitioner can use this book as a guide to the current understanding of retinal and choroidal cellular mechanisms involved in aging and disease. Beginning with a review of oxidative stress and inflammation in the pathoetiology of AMD and a review of the complement system in the retina, the book then takes a detailed look at oxidative stress in lipid metabolism and oxidized lipoproteins in the retina. It examines the anti-apoptotic activity of α-crystallins in the presence of glutathione, oxidative stress in the mitochondria and endoplasmic reticulum, the role of iron in retinal disease, the mechanisms of pathological VEGF expression, NAPDH oxidase mechanisms, and Hepatocyte Growth Factor in oxidative stress in the retina. A detailed look at the Ccl2-/-/Cx3cr1-/- mouse model of AMD follows. Then a detailed examination of the systemic changes in AMD is followed by a discussion of cerium oxide nanoparticle reduction of oxidative stress. Two chapters discuss progenitor cells in the cause and treatment of retinal diseases including AMD and diabetic retinopathy. Natural compounds in the prevention and treatment of retinal diseases are exhaustively presented, followed by a chapter on serotonin 5-HT1A receptor agonists in oxidative stress of the retina. The current anti-VEGF treatment strategies of neovascular AMD are then given. The volume continues with a detailed look at nitric oxide and inducible nitric oxide synthase in retinal vascular disease, an explanation of an in vivo technique of studying the effect of lipid hydroperoxides on circulating leucocytes in the retina, an excellent review of oxidative stress in retinopathy of prematurity, and a look at VEGF induced oxidative stress in the retinal ganglion cell. The book ends with a detail examination of the role of carotenoids in retinal health and disease. These 31 chapters summarize what is known about oxidative stress in retinal and choroidal disorders. All those involved with degenerative diseases of the eye will find Studies on Retinal and Choroidal Disorders to be illuminating and comprehensive.

Medical & VeterinaryBrances of medicineOphthalmology Publisher: Humana Press Inc. Publication Date: 17/02/2012 ISBN-13: 9781617796050  Details: Type: Hardback Format: Books
Availability: Printed to order. Despatched in 2-3 weeks.  

Robert D Stratton, MD is the Founder of Erie Retinal Surgery from 1984 to 2008 and past Head of the Division of Retinal Surgery, Department of Ophthalmology, University of Florida School of Medicine from 1980 to 1984 . He is a fellow of the American Board of Ophthalmology, the American Academy of Ophthalmology, and the American College of Surgeons. Dr. Stratton's interests include vitreous and retinal diseases and surgery, and has 30 years experience in clinical practice. He is currently Courtesy Assistant Professor in the Department of Ophthalmology, University of Florida and Adjunct Assistant Professor in the Division of Small Animal Clinical Sciences, School of Veterinary Medicine, University of Florida.William W Hauswirth , PhD, is the Rybaczki-Bullard Professor of Ophthalmology and Molecular Genetics at the University of Florida College of Medicine. Dr. Hauswirth is, in part, responsible for determining the mechanism of replication of adeno-associated virus (AAV) DNA and the discovery of mitochondrial DNA heteroplasmy in mammals, the basis of mitochondrial disease. He collaborated on the first successful rescue of a dominant genetic disease in animals and the first restoration of vision for a recessive retinal disease. He also demonstrated that AAV mediated gene therapy could cure red-green color blindness in monkeys. Dr Hauswirth's current interests involve the delivery and testing of potentially therapeutic genes for many eye diseases in natural and transgenic animal models of human disease.Thomas W. Gardner is Professor of Ophthalmology and Visual Sciences and Molecular and Integrative Physiology at the University of Michigan in Ann Arbor, Michigan. He was previously the Jack and Nancy Turner Professor of Ophthalmology and Cellular and Molecular Physiology at the Penn State College of Medicine. Dr. Gardner's interests include vitreoretinal diseases and surgery, and clinical and experimental diabetic retinopathy. He currently serves as Associate Editor of Diabetes and Acta Ophthalmologica and on the editorial board of the Journal of Ocular Biology, Diseases and Informatics. He served previously on the editorial board of Diabetes, and is the former Editor-in-Chief of Current Eye Research.

More books by Robert D. Stratton

More books by William W. Hauswirth

More books by Thomas W. Gardner

Leave Review

Delivery

Delivery Options

All delivery times quoted are the average, and cannot be guaranteed. These should be added to the availability message time, to determine when the goods will arrive. During checkout we will give you a cumulative estimated date for delivery.

Location 1st Book Each additional book Average Delivery Time
UK Standard Delivery FREE FREE 3-5 Days
UK First Class £4.50 £1.00 1-2 Days
UK Courier £7.00 £1.00 1-2 Days
Western Europe** Courier £17.00 £3.00 2-3 Days
Western Europe** Airmail £5.00 £1.50 4-14 Days
USA / Canada Courier £20.00 £3.00 2-4 Days
USA / Canada Airmail £7.00 £3.00 4-14 Days
Rest of World Courier £22.50 £3.00 3-6 Days
Rest of World Airmail £8.00 £3.00 7-21 Days

** Includes Austria, Belgium, Denmark, France, Germany, Greece, Iceland, Irish Republic, Italy, Luxembourg, Netherlands, Portugal, Spain, Sweden and Switzerland.

Delivery Help & FAQs

Returns Information

If you are not completely satisfied with your purchase*, you may return it to us in its original condition with in 30 days of receiving your delivery or collection notification email for a refund. Except for damaged items or delivery issues the cost of return postage is borne by the buyer. Your statutory rights are not affected.

* For Exclusions and terms on damaged or delivery issues see Returns Help & FAQs

You might also like

Ophthalmic Imaging: Posterior Segment...
(Paperback)
Christye Sisson
 
 
£110.00
 
Colour Atlas of Ophthalmic Plastic...
(Hardback)
Anthony G. Tyers; J. R. O. Collin
 
 
£199.99
 
Vitreoretinal Disorders in Primary Care
(Paperback)
Thomas H. Williamson
 
 
£61.99
 
Latest Blog
The Satisfaction of a Good Puzzle
21/11/2017

Alex Bellos extols the virtues of the puzzle, especially those from the great puzzle masters of Japan, and selects some of his favourite puzzle books.

#FoylesFive: Swap Snowflakes for Stardust
17/11/2017

Swap snowflakes for stardust this Christmas with some recommends that are out of this world, from Jamie-Lee from our Birmingham branch.

Read an extract of The Book of the Year
15/11/2017

Behold The Book of the Year, by the “No Such Thing As A Fish” podcasters a.k.a the QI Elves. The book is a surreal, silly and wonderful compendium of irreverent and topical facts that show 2017 in a unique light.

View all Blog Entries
Twitter
Show/Hide Tweets
© W&G Foyle Ltd