Enter your search into one or more of the boxes below:
You can refine your search by selecting from any of the options below:
Cryptosporidium Serology in Human Populations
Foyalty 382

Cryptosporidium Serology in Human Populations (Paperback)

Printed to order. Despatched in 2-3 weeks.
Email me when back in stock


The serological detection of antibodies to Cryptosporidium has emerged as a potential tool for population level studies. Second generation ELISA methods are known to detect immunoglobulin G (IgG) to two Cryptosporidium sporozoite surface antigens (apparent molecular mass 17 and 27 kDa). During 1996, 1,292 cases of cryptosporidiosis were reported to public health in the province of British Columbia in western Canada. This rate, seven times higher than that in 1995, was due to waterborne outbreaks occurring in this province. It was recognized that collection of serum specimens for study of the host immune response would be important and sera were collected from 41 adult volunteer cases associated with these outbreaks. A total of 232 sera were collected over a 24-month period. These Kinetics Cases sera were used to assess the host immune response. Sera from residents of six communities, some of which had outbreaks of cryptosporidiosis due to contamination of their drinking water, were also tested to determine the usefulness of serology at a population level.The first objective of this project was to determine the sensitivity of the second-generation enzyme linked immunosorbent assays (ELISA) developed at the Centers for Disease Control and Prevention (CDC) and of a previously described immunoblot assay. After that, the researchers planned to address some issues related to specificity of the ELISA. Then, the goal was to analyze changes in levels of antibody reactivity over time in persons with laboratory-confirmed cryptosporidiosis. The next objective was to compare initial results of the ELISA and immunoblot at a community level and further assess the usefulness of the ELISA at a population level by testing sera of residents of six communities, some of which had waterborne outbreaks of cryptosporidiosis. Finally, the researchers planned to evaluate the usefulness of saliva specimens for the detection of antibodies to Cryptosporidium using the ELISA assay. A serological approach appeared to be a useful epidemiological tool to assess cryptosporidiosis at the population level. The host immune response to both Cryptosporidium antigens was documented. The second generation CDC ELISA was the optimal format. The 17 kDa assay, in which the IgG response diminishes within 12 months, appeared to be a useful tool for studying recent events while the 27 kDa appeared to detect cumulative events. When applied to six communities (outbreak and non-outbreak), the seroprevalence within the communities varied. Outbreaks were detectable in some communities.Originally published by AwwaRF for its subscribers in 2003 This publication can also be purchased and downloaded via Pay Per View on Water Intelligence Online - click on the Pay Per View icon below

Medical & VeterinaryMedicine: general issuesPublic health & preventive medicineEpidemiology & medical statisticsTechnicalEnvironmental science, engineering & technologySanitary & municipal engineeringWater supply & treatment Publisher: IWA Publishing Publication Date: 01/01/2004 ISBN-13: 9781843398424  Details: Type: Paperback Format: Books
Availability: Printed to order. Despatched in 2-3 weeks.  

More books by J. Issac-Renton

More books by C. Ong

More books by W. Bowie

More books by P. Lammie

More books by J. Priest

Leave Review


Delivery Options

All delivery times quoted are the average, and cannot be guaranteed. These should be added to the availability message time, to determine when the goods will arrive. During checkout we will give you a cumulative estimated date for delivery.

Location 1st Book Each additional book Average Delivery Time
UK Standard Delivery FREE FREE 3-5 Days
UK First Class £4.50 £1.00 1-2 Days
UK Courier £7.00 £1.00 1-2 Days
Western Europe** Courier £17.00 £3.00 2-3 Days
Western Europe** Airmail £5.00 £1.50 4-14 Days
USA / Canada Courier £20.00 £3.00 2-4 Days
USA / Canada Airmail £7.00 £3.00 4-14 Days
Rest of World Courier £22.50 £3.00 3-6 Days
Rest of World Airmail £8.00 £3.00 7-21 Days

** Includes Austria, Belgium, Denmark, France, Germany, Greece, Iceland, Irish Republic, Italy, Luxembourg, Netherlands, Portugal, Spain, Sweden and Switzerland.

Delivery Help & FAQs

Returns Information

If you are not completely satisfied with your purchase*, you may return it to us in its original condition with in 30 days of receiving your delivery or collection notification email for a refund. Except for damaged items or delivery issues the cost of return postage is borne by the buyer. Your statutory rights are not affected.

* For Exclusions and terms on damaged or delivery issues see Returns Help & FAQs

You might also like

Rabies: Scientific Basis of the...
Alan C. Jackson
Bioemergency Planning: A Guide for...
Angela Hewlett; A. Rekha K. Murthy
Essential Concepts in Clinical...
Kenneth Schulz; David A. Grimes
Pandemic 1918: Eyewitness Accounts...
Catharine Arnold
© W&G Foyle Ltd
Foyles uses cookies to help ensure your experience on our site is the best possible. Click here if you’d like to find out more about the types of cookies we use.
Accept and Close