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Dna Repair, Genetic Instability, And Cancer
Foyalty 373

Dna Repair, Genetic Instability, And Cancer (Hardback)

£123.00
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Synopsis

This volume describes the elaborate surveillance systems and various DNA repair mechanisms that ensure accurate passage of genetic information onto daughter cells. In particular, it narrates how the cell cycle checkpoint and DNA repair machineries detect and restore DNA damages that are embedded in millions to billions of normal base pairs. The scope of the book ranges from biochemical analyses and structural details of DNA repair proteins, to integrative genomics and population-based studies. It provides a snapshot of current understanding about some of the major DNA repair pathways, including base-excision repair, nucleotide excision repair, mismatch repair, homologous recombination, and non-homologous end-joining as well as cell cycle checkpoints and translesion DNA synthesis. One of the particular emphases of the book is the link between inherited DNA repair deficiencies and susceptibility to cancer in the general population. For the first time, the book brings together a collection of review articles written by a group of active and laboratory-based investigators who have a clear understanding of the recent advances in the fields of DNA damage repair and genomic stability and their implications in carcinogenesis, new approaches in cancer therapy, and cancer prevention.

Medical & VeterinaryBrances of medicineDiseases & disordersOncologyMedical & VeterinaryBrances of medicineGene therapyMedical & VeterinaryPre-clinical medicine: basic sciencesMedical geneticsScience & MathematicsBiology, life sciencesLife sciences: general issuesBio-ethicsScience & MathematicsGeographyBiogeography Publisher: World Scientific Publishing Co Pte Ltd Publication Date: 09/01/2007 ISBN-13: 9789812700148  Details: Type: Hardback Format: Books
Availability: Currently unavailable to order online.  

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Location 1st Book Each additional book Average Delivery Time
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