Enter your search into one or more of the boxes below:
You can refine your search by selecting from any of the options below:
Gut-Associated Lymphoid Tissues
Foyalty 480

Gut-Associated Lymphoid Tissues (Hardback)

Usually despatched within 3 weeks.


The intestine is the front line of the confrontation between pathogens and the immune system. However, it is also important to emphasize that we have a symbiotic relationship with innumerable bacteria in the intestine. In the gastrointestinal tract of mammals the lower intestine harbors around 1,000 12 species of anaerobic and aerobic bacteria, in densities up to 10 /mlinthe distal small intestine, the cecum, and the colon. A single layer of epithelial cells of the intestine protects the internal organs of the mammalian host from these bacteria. Below these epithelial cells the gut-associated lymphoid tissues (GALT), organized in Peyer's patches, cryptopatches, and isolated l- phoid follicles, as well as isolated, dispersed single cells in the epithelial layer (intraepithelial lymphocytes) and lamina propria, are composed of T l- phocytes, B lymphocytes, Ig-secreting plasma cells, and antigen-presenting cells such as dendritic cells. The importance of the gut barrier is striking, if we consider that in humans the epithelial surface, behind which the immune system faces and senses the endogenous bacteria, is estimated to be as large as a basketball court.

Perhaps not surprising then, the gut contains appr- imately half of all lymphocytes of our immune system. Colonization of the intestine with the ?ora of commensal bacteria induces the development of the GALT, which in turn responds by the development of IgA-secreting plasma cells. Dimeric and multimeric IgAs can traverse the epithelial layer and are released in the gut lumen, where they bind bacteria.

Medical & VeterinaryBrances of medicineDiseases & disordersImmunology Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Publication Date: 10/07/2006 ISBN-13: 9783540306566  Details: Type: Hardback Format: Books
Availability: Usually despatched within 3 weeks. Add to Basket

More books by Tasuku Honjo

More books by Fritz Melchers

Leave Review


Delivery Options

All delivery times quoted are the average, and cannot be guaranteed. These should be added to the availability message time, to determine when the goods will arrive. During checkout we will give you a cumulative estimated date for delivery.

Location 1st Book Each additional book Average Delivery Time
Free UK Standard Delivery on Orders Over £20 (2nd Class)     3-5 Days
UK Standard Delivery (2nd Class) £2.75 £0.00 3-5 Days
UK 1st Class Delivery £3.75 £0.00 1-2 Days
Click and Collect / 
Delivery to a Foyles Bookshop
Free Free From 2 hours - Individual item delivery times given at checkout
UK Courier £7.95 £0.00 1 Working Day
Western Europe**Airmail £9.00 £1.00 7-8 Days
Rest of World Airmail £12.50 £1.00 7-10 Days

** Includes Austria, Belgium, Denmark, France, Germany, Greece, Iceland, Irish Republic, Italy, Luxembourg, Netherlands, Portugal, Spain, Sweden and Switzerland.

Click and Collect is available for all our shops; collection times will vary depending on availability of items. Individual despatch times for each item will be given at checkout.

Delivery Help & FAQs

A Year of Books Subscription Packages 

Delivery is free for the UK. Western Europe costs £60 for each 12 month subscription package purchased. For the Rest of the World the cost is £100 for each package purchased. All delivery costs are charged in advance at time of purchase. For more information please visit the A Year of Books page.

Returns Information

If you are not completely satisfied with your purchase*, you may return it to us in its original condition with in 30 days of receiving your delivery or collection notification email for a refund. Except for damaged items or delivery issues the cost of return postage is borne by the buyer. Your statutory rights are not affected.

* For Exclusions and terms on damaged or delivery issues see Returns Help & FAQs

You might also like

Surprise! It's Gluten Free!: 110...
Jennifer Fisher
Magnetic Triggered Drug Release: A...
Raghvendra Ashok Bohara
Biotechnology in the Modern Medicinal...
Rajesh K. Kesharwani; Krishna Misra
Ebola: Clinical Patterns, Public...
Joseph R. Masci; Elizabeth Bass
© W&G Foyle Ltd
Foyles uses cookies to help ensure your experience on our site is the best possible. Click here if you’d like to find out more about the types of cookies we use.
Accept and Close