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Non-Myeloablative Allogeneic Transplantation
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Non-Myeloablative Allogeneic Transplantation (Hardback)

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Synopsis

Non-myeloablative allogeneic stem cell transplantation (also known as mini-transplantation or reduced-intensity conditioning transplantation) is a major advance in the field of hematopoietic transplantation within the last 5 years. This approach uses non-cytotoxic or reduced-intensity cytotoxic therapy to prepare patients for allografting of hematopoietic stem cells and lymphocytes. It has the potential to deliver the potent anti-tumor immunotherapy and bone marrow replacement capacity of allogeneic stem cell transplantation to patients with reduced treatment-related morbidity and mortality. It may also enable allogeneic transplantation in patients who would be considered ineligible for conventional transplants because of co-morbidity or advanced age. However, this approach may necessitate more careful monitoring of post-transplant chimerism and malignant disease-status than is usual with conventional allografting. There is also controversy regarding the best preparative regimen and graft-versus-host disease prophylaxis to use.

Medical & VeterinaryBrances of medicineDiseases & disordersOncologyMedical & VeterinarySurgerySurgical oncology Publisher: Springer Publication Date: 28/02/2002 ISBN-13: 9780792376460  Details: Type: Hardback Format: Books
Availability: Currently unavailable to order online.  

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