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Protein Misfolding in Neurodegenerative Diseases: Mechanisms and Therapeutic Strategies
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Protein Misfolding in Neurodegenerative Diseases: Mechanisms and Therapeutic Strategies (Hardback)

£175.00
Usually despatched within 3 weeks.

Synopsis

Research focused on protein folding, misfolding, and aggregation is leading to major advances across biochemistry and medicine. The elucidation of a folding code is proving to be of extreme importance in the postgenomic era, where a number of orphan genes have been identified for which no clear function has yet been established. This research is starting to shed light on the molecular and biochemical basis of a number of neurodegenerative diseases of dramatic impact. Protein Misfolding in Neurodegenerative Diseases: Mechanisms and Therapeutic Strategies addresses key issues concerning protein misfolding and aggregation in neurodegenerative diseases. Building on recent developments, including the recognition of protein misfolding as both a marker and a causal agent, the text presents the work of those who are actively pursuing more effective treatments, as well as preventative measures, and a possible cure. These include the use of molecular chaperones to control misfolding and novel pharmaceuticals, as well as the potential role of various inhibitors and NSAIDS.



A Comprehensive Multifaceted Examination of the Complex Causal Agents Implicated in Protein Misfolding



Divided into five sections, this groundbreaking text provides up-to-date accounts for Alzheimer's, Parkinson's, Huntington's, Amyotrophic Lateral Sclerosis and Transmissible Spongiform Encephalitis. It also explores the highly likelihood that multiple factors, including oxidative stress, play a role in these complex diseases.

Medical & VeterinaryBrances of medicineNeurology & clinical neurophysiologyMedical & VeterinaryPre-clinical medicine: basic sciencesMedical & VeterinaryPre-clinical medicine: basic sciencesAnatomyCytologyMedical & VeterinaryPre-clinical medicine: basic sciencesAnatomyHistologyScience & MathematicsChemistry Publisher: Taylor & Francis Inc Publication Date: 03/12/2007 ISBN-13: 9780849373107  Details: Type: Hardback Format: Books
Availability: Usually despatched within 3 weeks. Add to Basket

H. John Smith, Claire Simons, Robert D. E. Sewell

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