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Qualite De Vie Liee a L'Etat De Sante: Critere D'Evaluation: Health-Related Quality of Life and Patient-Reported Outcomes: Scientific and Useful Outcome Criteria
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Qualite De Vie Liee a L'Etat De Sante: Critere D'Evaluation: Health-Related Quality of Life and Patient-Reported Outcomes: Scientific and Useful Outcome Criteria (Hardback)

£36.50
Usually despatched within 3 weeks.

Synopsis

Apres plusieurs decennies de recherche, le critere "qualite de vie liee a l'etat de sante" est probablement a la croisee des chemins dans le domaine de l'evaluation therapeutique. Il s'integre dans le cadre plus large des "Patient-Reported Outcomes". En effet, l'evaluation par le patient lui-meme de l'efficacite et de la tolerance des medicaments dans un nombre croissant de pathologies, notamment chroniques, appara t essentielle. L'introduction precise et justifie les situations et pathologies dans lesquelles la mesure de la qualite de vie apporte une information qui ne peut etre mesuree correctement par les criteres d'evaluation habituels cliniques, biologiques ou physiologiques. La premiere partie du livre, rapporte l'etat de la science quant a la definition et au developpement des questionnaires de qualite de vie et des "Patient-Reported Outcomes". Elle precise les necessites de l'adaptation culturelle et de la validation psychometrique des questionnaires dans le cadre d'essais cliniques internationaux.

Elle rapporte les recommandations pratiques d'un groupe de travail multidisciplinaire (ERIQA, European Regulatory Issues on Quality of Life Assessment) sur la mesure de ces criteres dans les essais cliniques. L'application de ces concepts est illustree dans le domaine de la pathologie rhumatologique, par une revue des questionnaires generiques et specifiques disponibles. La deuxieme partie confronte les arguments des acteurs impliques dans l'enregistrement du medicament: industriel, et representants des Agences francaise et europeenne (AFSSAPS, EMEA), et de la FDA americaine. Elle permet de mieux cerner les conditions dans lesquelles les autorites d'enregistrement peuvent accepter les etudes de qualite de vie. La lecture du livre laisse entrevoir, des maintenant, une place centrale du patient dans les prises de decision therapeutique. En depit de leur approche parfois differente, tous les auteurs du livre emploient un meme mot: celui de rigueur (methodologique, logistique, d'analyse et d'interpretation). C'est a cette exigence que le critere qualite de vie gardera toute sa credibilite scientifique.

Medical & VeterinaryBrances of medicinePharmacologyMedical & VeterinaryMedicine: general issuesHealth systems & servicesMedical & VeterinaryMedicine: general issuesMedical equipment & techniquesMedical laboratory testing & techniquesMedical & VeterinaryNursing & ancillary servicesPharmacy / dispensing Publisher: Springer Editions Publication Date: 01/10/2002 ISBN-13: 9782287597763  Details: Type: Hardback Format: Books
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