Enter your search into one or more of the boxes below:
You can refine your search by selecting from any of the options below:
Introduction to Perfusion Quantification using Arterial Spin Labelling
Foyalty 70

Introduction to Perfusion Quantification using Arterial Spin Labelling (Paperback)

Despatched in 2 business days.


Arterial Spin Labeling (ASL) is an increasingly popular tool to study the brain. What sets it apart from other neuroimaging methods is the combination of quantitative measurements of a physiologically well-defined process, namely perfusion, and a completely non-invasive acquisition methodology.

Cerebral perfusion is a critical component to brain health, as it is the primary means to deliver nutrients to support brain function as well as clearing waste products. Hence it is a useful quantity to study in disease where changes in perfusion can indicate regions of the brain that are pathological. Likewise changes in perfusion can be indicative of greater demand for nutrients, such as might be required in response to an increase in neuronal activity.

With the advent of a consensus by the ASL community on good practice and a recommendation on robust methods for ASL data collection, more and more researchers are now able to access and use ASL. Despite the technological advances, ASL remains a technique with a low signal to noise ratio. This makes the wise choice of the appropriate analysis methods more important.

The aim of this primer is to equip someone new to the field of perfusion imaging and ASL with the knowledge not only to make good choices about ASL acquisition and analysis, but also to understand what choices they are making and why. Examples of analysis applied to real data are given throughout the text and instructions on how to reproduce the analyses are illustrated on the primer website.

Written to provide a stand-alone introduction to perfusion qualification using ASL, this primer also works with other texts in the Oxford Neuroimaging Primers series to provide a comprehensive overview of the increasingly influential field of neuroimaging.

Michael Chappell is head of the Quantitative Biomedical Inference group at the Institute of Biomedical Engineering, University of Oxford. He specialises in methods to infer physiological and metabolic information such as perfusion and pH from medical imaging data. These methods are applied in a wide range of medical applications including stroke, dementia and cancer. Michael is also the Director of Training for the EPSRC-MRC Centre for Doctoral Training in Biomedical Imaging. Prior to working in medical image analysis, Michael did a doctorate in SCUBA diving and for a short while investigated methods to identify buried objects such as landmines. Brad MacIntosh runs a lab focused on perfusion and vascular imaging at Sunnybrook Research Institute, University of Toronto. Brad pursued Masters and PhD work in the department of Medical Biophysics at the University of Toronto and Western University. His postdoc was at the FMRIB Centre in Oxford. Brad works on clinical translation of BOLD and ASL functional MRI to a wide range of brain diseases. He also uses these techniques to understand the acute and chronic effects of aerobic exercise on the brain. Thomas Okell is the head of neurovascular imaging research within the physics group at the Oxford Centre for Functional MRI of the Brain (FMRIB). His research focuses on the development of non-invasive MRI methods to visualise the flow of blood through the arteries and the resulting perfusion of the brain tissue. These methods are being applied in a range of patient groups, including those with acute stroke and arteriovenous malformation. Thomas is also the director of physics education for the FMRIB graduate program. He trained as a medical physicist within the NHS before discovering the joys of arterial spin labelling during his PhD.

More books by Michael Chappell

More books by Bradley MacIntosh

More books by Thomas Okell

Leave Review


Delivery Options

All delivery times quoted are the average, and cannot be guaranteed. These should be added to the availability message time, to determine when the goods will arrive. During checkout we will give you a cumulative estimated date for delivery.

Location 1st Book Each additional book Average Delivery Time
UK Standard Delivery FREE FREE 3-5 Days
UK First Class £4.50 £1.00 1-2 Days
UK Courier £7.00 £1.00 1-2 Days
Western Europe** Courier £17.00 £3.00 2-3 Days
Western Europe** Airmail £5.00 £1.50 4-14 Days
USA / Canada Courier £20.00 £3.00 2-4 Days
USA / Canada Airmail £7.00 £3.00 4-14 Days
Rest of World Courier £22.50 £3.00 3-6 Days
Rest of World Airmail £8.00 £3.00 7-21 Days

** Includes Austria, Belgium, Denmark, France, Germany, Greece, Iceland, Irish Republic, Italy, Luxembourg, Netherlands, Portugal, Spain, Sweden and Switzerland.

Click and Collect is available for all our shops; collection times will vary depending on availability of items. Individual despatch times for each item will be given at checkout.

Special delivery items

A Year of Books Subscription Packages 

Delivery is free for the UK. Western Europe costs £60 for each 12 month subscription package purchased. For the Rest of the World the cost is £100 for each package purchased. All delivery costs are charged in advance at time of purchase. For more information please visit the A Year of Books page.

Animator's Survival Kit

For delivery charges for the Animator's Survival Kit please click here.


Delivery Help & FAQs

Returns Information

If you are not completely satisfied with your purchase*, you may return it to us in its original condition with in 30 days of receiving your delivery or collection notification email for a refund. Except for damaged items or delivery issues the cost of return postage is borne by the buyer. Your statutory rights are not affected.

* For Exclusions and terms on damaged or delivery issues see Returns Help & FAQs

You might also like

Cardiovascular Magnetic Resonance: A...
Warren J. Manning; Dudley J. Pennell
Duke Review of MRI Physics: Case...
Wells Mangrum; Quoc Bao Phil B Hoang;...
© W&G Foyle Ltd
Foyles uses cookies to help ensure your experience on our site is the best possible. Click here if you’d like to find out more about the types of cookies we use.
Accept and Close