The Chlamydomonas Sourcebook: Cell Motility and Behavior: Volume 3 - Susan Dutcher; | Foyles Bookstore
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The Chlamydomonas Sourcebook: Cell Motility and Behavior: Volume 3
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The Chlamydomonas Sourcebook: Cell Motility and Behavior: Volume 3 (Hardback)

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The Chlamydomonas Sourcebook, Third Edition, Volume Three: Cell Motility and Behavior has been fully revised and updated to include the wealth of new resources for the Chlamydomonas community. The book presents the latest advances in the area from an international array of expert authors, reflecting significant advancements in our understanding of the role of basal bodies and flagella in human diseases. In addition, employing quantitative proteomics/mass spectroscopy as well as cryo EM tomography and single particle cryo EM has revolutionized our knowledge of the axoneme in terms of the location of proteins and their interactions.

Current insights on mitosis and cytokinesis, flagellar assembly and motility, intraflagellar transport, and more will ensure use of this reference as a guide for understanding human diseases of the cilium.

Science & MathematicsBiology, life sciencesBotany & plant sciencesPhycology, algae & lichensScience & MathematicsBiology, life sciencesCellular biology or cytologyScience & MathematicsBiology, life sciencesMicrobiology non-medicalScience & MathematicsBiology, life sciencesMolecular biology Publisher: Elsevier Science Publishing Co Inc Publication Date: 01/05/2022 ISBN-13: 9780128225080  Details: Type: Hardback Format: Books
Availability: Pre-order for despatch on publication. Pre-Order

Susan K. Dutcher is Professor and was Director of the McDonnell Genome Institute at Washington University School of Medicine. Her lab investigates the assembly and function of basal bodies/centrioles and cilia using genetics, biochemistry, microscopy, and computational biology in Chlamydomonas as well as human tissue culture cells. The key questions that they address are how these microtubule-based structures are assembled, how they are regulated with respect to the cell cycle and how they function and influence cellular biology, development, and human health. Stemming from their comparative genomics work in 2004, the discovery of many cilia and centriole-based diseases has illustrated the incredible breath of roles that these organelles play in human health. While no longer Director, she remains as the PI of a grant she obtained to build better human and nonhuman primate references, also bringing in underrepresented minorities as undergraduates to expose them to genomics research during the summer.

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