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The Mechanisms of Neuronal Damage in Virus Infections of the Nervous System
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The Mechanisms of Neuronal Damage in Virus Infections of the Nervous System (Paperback)

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Synopsis

It has been recognized that viruses can induce neuronal damage by a variety of mechanisms. This volume summarizes, for the first time, the various ways that neurons can degenerate under the influence of viral infection, ranging from acute necrosis and virus-induced apoptosis to chronic damage in persistent infections. The mechanisms of neuronal latency are dealt with as well. The volume also includes chapters that review the chronic damage caused by viral proteins that interfere with differentiated functions of the neuron, including signaling by neurotransmitters and signal transduction by trophic factors. Other chapters deal with the controversial role of cellular immune reactions, which may be helpful in controlling infection, but may also be detrimental to the host nervous system. The specific mechanisms of damage involved in retroviral infections and in prion diseases of the nervous system are reviewed, and finally how autoimmune diseases can lead to neuronal damage.

Medical & VeterinaryBrances of medicineDiseases & disordersImmunologyMedical & VeterinaryBrances of medicineNeurology & clinical neurophysiologyMedical & VeterinaryBrances of medicinePathologyMedical microbiology & virologyScience & MathematicsBiology, life sciencesLife sciences: general issuesNeurosciences Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Publication Date: 05/12/2010 ISBN-13: 9783642087103  Details: Type: Paperback Format: Books
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